Posts Tagged ‘onchocerciasis’

Reading List 3/8/2010

March 8th, 2010

Today, as we join in celebrating International Women’s Day, we’re reading the WHO’s comments on this day as well as reviewing a paper Dr. Peter Hotez wrote about womens health and NTDs. We’re also reading a profile of river blindness and about Buruli ulcer, one of the less discussed NTDs.

Equal rights, equal opportunities: progress for all, World Health Organization

WHO laments “shameful” lack of respect for women’s right to good health, World Health Organization

Empowering Women and Improving Female Reproductive Health through Control of Neglected Tropical Diseases, Peter Hotez, PLoS Neglected Tropical Diseases

Blind to the river and its hazards, Stanley M. Aronson, The Providence Journal

Buruli ulcer: an overlooked tropical disease, Robert Herriman, Examiner.com

River Blindness Transmission Cycle Broken in Ecuador

March 4th, 2010

Just this week the Ministry of Health and several other partners in the Onchocerciasis Elimination Program for the Americas (OEPA) have declared onchocerciasis transmission has been halted in Ecuador. As per World Health Organization policy, Ecuador must now monitor and verify elimination for the next three years. In 2008, the Pan American Health Organization restated its dedication to eliminating river blindness in the Americas by 2012 and this announcement is an important step towards achieving that goal.

Onchocerciasis is transmitted by the bite of the black fly and a small, bite-transmitted worm parasite. This parasite, Onchocerca volvulus, causes skin irritation and can cause loss of sight. The illness is known as river blindness because the black flies breed in fast-moving bodies of water near affected communities. In order to break the disease transmission cycle, implementing organizations utilize the common practice of mass drug administration (MDA). In MDA programs, safe and affordable (often donated) drugs are distributed to entire communities several times a year. For onchocerciasis treatments, the Merck produced drug Mecitzan (ivermectan) is used at no cost. In the last twenty years over eight million doses have been distributed across the region in endemic communities.

OEPA is a regional collaboration that was started in 1993 by The Carter Center to treat the more than 500,000 people at risk for this disease across Latin America. The partnership includes the Pan American Health Organization (World Health Organization), the pharmaceutical company Merck, the Pan American Health and Education Foundation (PAHEF), Lions Clubs International Foundation, and the Bill and Melinda Gates Foundation. The OEPA program targets the six Latin American countries (Brazil, Ecuador, Guatemala, Mexico and Venezuela) where onchocerciasis is still a public health threat. Originally there were seven countries on this list, but Colombia achieved transmission interruption in 2008. In light of this week’s announcement, this list will be shortened to only five countries.

With a growing interest in the potential for elimination of onchocerciasis from Africa, the success of the programs in the Americas provides an experience base that can guide the next phase of the onchocerciasis program in Africa.

See Also: 

http://www.pahef.org/press/2010_river_blindness.html

http://www.aolnews.com/health/article/ecuador-halts-spread-of-river-blindness/19378514

http://www.cartercenter.org/news/pr/ecuador-030110.html

Good Read: Ending the Neglect of Neglected Tropical Diseases

February 19th, 2010

Here is some worthwhile weekend reading! Perfect for lounging out and sipping a cup of tea at a local coffee shop!

 The Population Research Bureau (PRB) put out a policy brief called “Ending the Neglect of Neglected Tropical Diseases.” The paper gives a good introduction and breakdown of NTDs, its global impact and the cost-effective and efficient solutions available now to help tackle them.

Check it out here

Neglected Tropical Diseases and the Quest for Social Justice

February 19th, 2010

Tomorrow, February 20th, 2010, marks the second annual World Day of Social Justice. This event was created in 2007 to “consolidate further the efforts of the international community in poverty eradication and in promoting full employment and decent work, gender equality and access to social well-being and justice for all.” There are many ways to work towards those goals, but one of the most effective, and cost effective, is the elimination of neglected tropical diseases (NTDs).

 To eradicate poverty and promote full employment, NTD treatment is vital in the developing world. If a person is suffering from lymphatic filariasis and has severely swollen limbs to the point of being unable to work, or have contracted trachoma or onchocerciasis and gone blind, it hinders their ability to earn a living. Infections from the soil-transmitted helminth family of parasites cause anemia and nutrient deficiencies in children, stunting their physical and mental development. One of these parasites, roundworm, can decrease the future earnings potential of an infected child by 43%. However, deworming not only prevents the developmental disabilities created by infection, but also has been found to decrease school absenteeism by 25%. If future generations are to break free of the vicious cycle of poverty and unemployment, then NTD treatment must be included in any efforts.

Photo courtesy of Lindsay Wheeler

Photo courtesy of Lindsay Wheeler

 NTDs also play heavily into issues of gender equality, as they tend to disproportionately affect women. In areas of great gender inequality, the social stigmas attached to the disfigurement, morbidity, and disability caused by NTDs tend to be especially isolating and ostracizing for women. Women who have suffered from disfiguring NTDs such as lymphatic filariasis or onchoerciasis have lost their jobs, lost their families, and even been prevented from seeking medical attention. Further, NTDs pose special risks to women sexually and reproductively.  NTD infections cause women in particular to be especially at risk for sexually transmitted diseases. Genital sores on women caused by schistosomiasis have been shown to increase the risk of HIV infection threefold. Both schistosomiasis and roundworm have been linked to maternal anemia during pregnancy, leading to complications, as well as low birth weight and sterility. For gender equality to be reached, these diseases which disproportionately affect women must be dealt with.

 Those two points together make a strong case for NTD treatment, but there’s even more to be said in terms of social well-being and justice. Nations which are unstable or volatile, such as Pakistan, Niger, or Sudan, tend to have a high NTD disease burden. That is no coincidence. NTDs breed the poverty and inequality that give rise to political instability and violence. NTD treatment would not only heal the sick and help the poor, but it would help to stabilize nations and entire regions.

 So tomorrow, as you enjoy your Saturday, remember those less fortunate than you. Remember those for whom survival is a daily struggle, poverty an unavoidable fact of life, and political instability and violence an ever present threat. Then consider that treatment for the seven most common NTDs can be provided for only 50 cents a year per person. Consider all the good that can be done for such a small price.

 The UN created World Day of Social Justice with an eye towards a better future. For that to be accomplished, NTD treatment must be part of the plan.

Reading List for 2/17/10

February 17th, 2010

Today we’re reading about some exciting developments in dealing with insect-borne diseases, updates on the prevalence of blinding diseases in Africa, and the start of the UN’s annual conference with NGO’s focusing on global health.

Posing Proteins: First Chikungunya Vaccine Tested on Monkeys Successfully, Down to Earth

Mosquito Nose Transplants Help Fight Malaria, Catharine Paddock, Medical News Today

Bednets to Stop Leishmaniasis Spread, Smriti Mallapaty, SciDevNet

Blinding Infectious Disease is More Common in Malawi Than Anticipated, Paul Chinnock, TropIKA

Ghana: Krachiwura’s SOS Message to Govt, Samuel Agbewode, AllAfrica.com

UN’s Annual Conference with Civil Society Groups to Spotlight Global Health Issues, UN News Centre

Reading List 2/16/10

February 16th, 2010

Today we’ve got some exciting news about possible cures for NTDs, Obama’s new envoy focusing on global health, and a bit of science looking at a past success. Here’s what we’re reading today:

UCSF may have cure for deadly disease Chagas, Carol Lloyd, San Francisco Chronicle

How an Old Drug Could Have a New Use for Treating River Blindness, Science Daily

In Naming Islamic Conference Envoy, Obama Highlights Global Health, Food Security Efforts, Kaiser Family Foundation

Successful Control of Lymphatic Filariasis in the Republic of Korea, multiple authors, The Korean Society for Parasitology

Reading List 2/12/10

February 12th, 2010
DC Streets Covered in a Blanket of Snow
DC Streets Covered in a Blanket of Snow

As we dig ourselves out and are settling back into the office after unprecedented amount of snow hit Washington DC this past week, here is what we’ve been reading.

  1. Former U.S. President Jimmy Carter Visits Last Stronghold of Guinea Worm Disease in Southern Sudan, Emily Staub, ModernGhana.com
  2. Drug shows promise against river blindness, Yahoo! News
  3. What Haiti needs most, Richard Santos, Baltimore Sun
  4. Hong Kong Says Skip Worm Diet, Scott Hensley, NPR Blog
  5. Uganda: Swelling Feet Bring Pain, Fear to Ibanda Village, Jennina Aryampwera, allAfrica.com
  6. Halving world poverty by 2015 unlikely: UN, AFP
  7. Aid groups fear Haitian relief diverts funds from other needs, Mary Beth Sheridan, Washington Post

New Scientific Paper Examines the Lack of Scientific Interest in Neglected Tropical Diseases

February 3rd, 2010

As part of the global health community, we are always working to raise the profile of the neglected tropical diseases. 

A paper  released in the January 26th, 2010 edition of the online peer-reviewed scientific journal PLoS Neglected Tropical Diseases, looks at the lack of research and attention given to the NTDs.  Author Dieter Vanderelst,an economist at the University of Antwerp, argues that scientific research into the NTDs lags behind other diseases which have a similar burden around the world. Not only does this disparity exist, but it is likely underestimated.

The researchers write that, “The disproportionally low research interest in NTDs is doubly worrying if one considers that the DALYs associated with NTDs are generally assumed to be underestimated.” DALYs are a public health measurement that takes into account the years of life a person loses due to either illness or death from a specific disease. Although there has been measurable growth in the body of research around the NTDs, this has been largely attributed to the creation of the NTD specific PloS journal.

Similarly, resources for NTDs are growing due to the increased interest in global health and now many new partners are working on cost effective and efficient solutions and interventions.  “It will be necessary for civil society, scientists, and policymakers alike to break this cycle so that some of the most common infections among the 2.7 billion people living on less than US$ 2 per day receive the attention they deserve.” Although progress is being made, there is still a lot of work to be done.

With the release of President Obama’s proposed FY11 budget allocating $155 million towards NTD control and elimination efforts it seems as if the Administration is making NTDs a significant priority. In particular, the Administration is seeking to reduce the prevalence of NTDs globally by 50% within 70% of all of the affected population, eliminate onchocerciasis in Latin America by 2016, eliminate lymphatic filariasis globally by 2017, and eliminate leprosy globally. With this new focus on NTDs, and the associated increase in resources, perhaps the research gap for NTDs will begin to close.

Reading List 2/2/10

February 2nd, 2010

With the release of Obama’s proposed FY11 budget yesterday and the $155 million allocated to NTDs specifically, we’re reading many different articles about the Administration’s 9% increase in global health funding. We’re also reading about the recent $13 million grant that the Gates Foundation has given to The Washington University School of Medicine in St. Louis to eliminate  elephantiasis (lymphatic filariasis) and river blindness (onchocerciasis), in the developing world. Lots of exciting things happening for the NTD community!

  1. White House Proposes 9% Increase in Global Health Funding, Betsy McKay, WSJ
  2. Obama Boosts Funding for Tropical Diseases, Maggie Fox, Reuters
  3. Obama Budget Aids War Zones, Global Health Programs (Update1) , Indira A.R. Lakshmanan, Bloomberg
  4. Extra Money for Science in Obama’s Budget, Donald McNeil, New York Times
  5. The President’s Budget: Neglected Tropical Diseases, Erin Hohlfelder, ONE.org Blog
  6. Gates Foundation Commits $13 Million to Eliminate Two Tropical Diseases, Philanthropy News Digest
  7. The Gates Foundation’s expansion of its support, and the thinking that lies behind it, Paul Chinnock, TropIKA.net

Scientific American Magazine Spotlights NTDs

December 17th, 2009

NTDs get major news attention in the January 2010 issue of Scientific American Magazine.  The issue features an article titled “How to Cure 1 Billion People—Defeat Neglected Tropical Diseases (NTDs)” by our very own Peter Hotez, detailing the disease burden of NTDs around the world, and the simple, cost effective solutions available for their prevention and control.  The article is an informative teaching tool for those unfamiliar with NTDs and also presents a clear call to action: now is the time to act to end the neglect of NTDs. Now, more than ever, the global health community is positioned to tackle NTDs. However, Hotez argues that despite enormous successes with mass drug administration programs and increased awareness and funding, we still have a long way to go to provide complete drug coverage for the billion or more people with NTDs.

Here is an excerpt of the article:

“In the north of Burkina Faso, not far to the east of one of the best-known backpacker destinations in West Africa, the Bandiagara Escarpment in Mali, lies the town of Koumbri. It was one of the places where the Burkina Ministry of Health began a mass campaign five years ago to treat parasitic worms. One of the beneficiaries, Aboubacar, then an eight-year-old boy, told health workers he felt perpetually tired and ill and had noticed blood in his urine. After taking a few pills, he felt better, started to play soccer again, and began focusing on his schoolwork and doing better academically.”


“The Burkina Faso program, which treated more than two million children, was both a success story and an emblem of the tragedy of disease in the developing world. For want of very simple treatments, a billion people in the world wake up every day of their lives feeling sick. As a result they cannot learn in school or work effectively.”

Visit our website to read the full article or pick up your own copy when it hits newsstands in January.